p creb p atf1 (Cell Signaling Technology Inc)
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p creb p atf1
P Creb P Atf1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 2150 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phospho-creb/Phospho-CREB+(Ser133)+Rabbit+mAb/pmc13000455-190-13-14
Average 97 stars, based on 2150 article reviews
P Creb P Atf1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 2150 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/phospho-creb/Phospho-CREB+(Ser133)+Rabbit+mAb/pmc13000455-190-13-14
Average 97 stars, based on 2150 article reviews
p creb p atf1 - by Bioz Stars,
2026-10
97/100 stars
Images
1) Product Images from "Transient SUMOylation inhibition in human pre-adipocytes stably imprints a transcriptional beiging fate"
Article Title: Transient SUMOylation inhibition in human pre-adipocytes stably imprints a transcriptional beiging fate
Journal: Nucleic Acids Research
doi: 10.1093/nar/gkag232
Figure Legend Snippet: Effect of transient SUMOylation inhibition in pre-adipocytes on cAMP-PKA-p38 signaling and adaptive thermogenesis in mature adipocytes. ( A ) Heatmap showing the stable upregulation of most genes involved in adaptive thermogenesis and cAMP-PKA-p38 signaling 22 days after adipogenic induction. Z -scores were calculated and plotted in GraphPad Prism. Treatments of pre-adipocytes were performed as shown in Fig. . ( B ) Western blot analysis of PKA substrates phosphorylation, assessed using a pan-PKA-target antibody, 22 days after adipogenic induction. TBP was used as a loading control. The asterisk (*) indicates substrates significantly affected by TAK-981 and/or rosiglitazone treatment. ( C ) Quantification of PKA substrate signals from panel (B). The signal for PKA substrates and TBP was quantified using Fiji software, with PKA substrate signals normalized to TBP. Error bars represent the standard deviation of four independent experiments. Student’s t -test was used to calculate P -values. ( D ) Western blot analysis of p-CREB, p-ATF1, p38, p-p38, and p-ATF2, 22 days after adipogenic induction. TBP was used as a loading control. ( E ) Quantification of p-CREB/ATF-1 signals from panel (D). Signals were normalized to TBP. Error bars represent the standard deviation of three independent experiments. Student’s t -test was used to calculate P -values. ( F ) Western blot analysis of p-CREB in the absence or presence of the PKA inhibitor RP-8-CPT-cAMPS. TBP was used as a loading control. Quantification of p-CREB, normalized to TBP, is showed in the lower panel. Error bars represent the standard deviation of two independent experiments. Quantification of p-p38 ( G ) and p-ATF2 ( H ) from experiment in panel (D). Signals were normalized to TBP for p-ATF2 and to p38 for p-p38. Error bars represent the standard deviation of three independent experiments. Student’s t -test was used to calculate P -values.
Techniques Used: Inhibition, Western Blot, Phospho-proteomics, Control, Software, Standard Deviation
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However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and Protease Inhibitor:Article Title: Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation. Article Snippet: Adult neurogenesis in hippocampus dentate gyrus (DG) is associated with numerous neurodegenerative diseases such as aging and Alzheimer’s disease (AD).. Overactivation of microglia induced neuroinflammation is well acknowledged to contribute to the impaired neurogenesis in pathologies of these diseases and then leading to cognitive dysfunction.. Histamine H3 receptor (H3R) is a presynaptic autoreceptor regulating histamine release via negative feedback way. Article Title: Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells Article Snippet: The primary antibodies used were as follows: CREB, Phospho-CREB, p38, Phospho-p38, Article Title: Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts. Article Snippet: Mouse enzyme-linked immunosorbent assay (ELISA) kits were purchased from Boster Biological Technology, Wuhan, China; TRIzol reagent was from Ambion, Austin, TX, USA; RevertAidTM M-MuLV reverse transcriptase was from Fermentas, NY, Amherst, USA; FastStart Universal SYBR Green Master (Rox) was from Roche Diagnostics, Indianapolis, IN, USA; cyclic 3′,5′-adenosine monophosphate (cAMP) assay kit was from Jiancheng Bioengineering Institute, Nanjing, China; Fluo-3 AM was from Dojindo Laboratories, Kumamoto, Japan; reactive oxygen species (ROS) assay kit, radioimmunoprecipitation assay (RIPA) lysis buffer, enhanced chemiluminescence (ECL) kit, bicinchoninic acid (BCA) protein assay kit, horseradish peroxidase (HRP)-conjugated anti-rabbit and anti-mouse IgG were from Beyotime Biotech, Nantong, China; protease inhibitor and phosphatase inhibitor were from Bimake, Houston, TX, USA; anti-rabbit p38 MAPK, phospho-p38 MAPK, p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK, NF-κB p65, phosphor-NF-κB p65, CREB, phospho-CREB, COX2, and Article Title: Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression. Article Snippet: Ethnopharmacological relevance: Uncaria rhynchophylla ([Mi] Jack) (gouteng) exerts antidepressive effects.. Rhynchophylline (RH), a major component of U. rhynchophylla, exerts similar pharmacological effects to those of gouteng.. Thus, RH may have antidepressive effects. Article Title: Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway Article Snippet: The primary antibodies used in this experiment were Article Title: Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Article Snippet: Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites.. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM).. However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and Blocking Assay:Article Title: Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation. Article Snippet: Adult neurogenesis in hippocampus dentate gyrus (DG) is associated with numerous neurodegenerative diseases such as aging and Alzheimer’s disease (AD).. Overactivation of microglia induced neuroinflammation is well acknowledged to contribute to the impaired neurogenesis in pathologies of these diseases and then leading to cognitive dysfunction.. Histamine H3 receptor (H3R) is a presynaptic autoreceptor regulating histamine release via negative feedback way. Article Title: Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells Article Snippet: The primary antibodies used were as follows: CREB, Phospho-CREB, p38, Phospho-p38, Article Title: Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts. Article Snippet: Mouse enzyme-linked immunosorbent assay (ELISA) kits were purchased from Boster Biological Technology, Wuhan, China; TRIzol reagent was from Ambion, Austin, TX, USA; RevertAidTM M-MuLV reverse transcriptase was from Fermentas, NY, Amherst, USA; FastStart Universal SYBR Green Master (Rox) was from Roche Diagnostics, Indianapolis, IN, USA; cyclic 3′,5′-adenosine monophosphate (cAMP) assay kit was from Jiancheng Bioengineering Institute, Nanjing, China; Fluo-3 AM was from Dojindo Laboratories, Kumamoto, Japan; reactive oxygen species (ROS) assay kit, radioimmunoprecipitation assay (RIPA) lysis buffer, enhanced chemiluminescence (ECL) kit, bicinchoninic acid (BCA) protein assay kit, horseradish peroxidase (HRP)-conjugated anti-rabbit and anti-mouse IgG were from Beyotime Biotech, Nantong, China; protease inhibitor and phosphatase inhibitor were from Bimake, Houston, TX, USA; anti-rabbit p38 MAPK, phospho-p38 MAPK, p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK, NF-κB p65, phosphor-NF-κB p65, CREB, phospho-CREB, COX2, and Article Title: Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression. Article Snippet: Ethnopharmacological relevance: Uncaria rhynchophylla ([Mi] Jack) (gouteng) exerts antidepressive effects.. Rhynchophylline (RH), a major component of U. rhynchophylla, exerts similar pharmacological effects to those of gouteng.. Thus, RH may have antidepressive effects. Article Title: Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway Article Snippet: The primary antibodies used in this experiment were Article Title: Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Article Snippet: Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites.. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM).. However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and Incubation:Article Title: Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation. Article Snippet: Adult neurogenesis in hippocampus dentate gyrus (DG) is associated with numerous neurodegenerative diseases such as aging and Alzheimer’s disease (AD).. Overactivation of microglia induced neuroinflammation is well acknowledged to contribute to the impaired neurogenesis in pathologies of these diseases and then leading to cognitive dysfunction.. Histamine H3 receptor (H3R) is a presynaptic autoreceptor regulating histamine release via negative feedback way. Article Title: Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells Article Snippet: The primary antibodies used were as follows: CREB, Phospho-CREB, p38, Phospho-p38, Article Title: Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts. Article Snippet: Mouse enzyme-linked immunosorbent assay (ELISA) kits were purchased from Boster Biological Technology, Wuhan, China; TRIzol reagent was from Ambion, Austin, TX, USA; RevertAidTM M-MuLV reverse transcriptase was from Fermentas, NY, Amherst, USA; FastStart Universal SYBR Green Master (Rox) was from Roche Diagnostics, Indianapolis, IN, USA; cyclic 3′,5′-adenosine monophosphate (cAMP) assay kit was from Jiancheng Bioengineering Institute, Nanjing, China; Fluo-3 AM was from Dojindo Laboratories, Kumamoto, Japan; reactive oxygen species (ROS) assay kit, radioimmunoprecipitation assay (RIPA) lysis buffer, enhanced chemiluminescence (ECL) kit, bicinchoninic acid (BCA) protein assay kit, horseradish peroxidase (HRP)-conjugated anti-rabbit and anti-mouse IgG were from Beyotime Biotech, Nantong, China; protease inhibitor and phosphatase inhibitor were from Bimake, Houston, TX, USA; anti-rabbit p38 MAPK, phospho-p38 MAPK, p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK, NF-κB p65, phosphor-NF-κB p65, CREB, phospho-CREB, COX2, and Article Title: Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression. Article Snippet: Ethnopharmacological relevance: Uncaria rhynchophylla ([Mi] Jack) (gouteng) exerts antidepressive effects.. Rhynchophylline (RH), a major component of U. rhynchophylla, exerts similar pharmacological effects to those of gouteng.. Thus, RH may have antidepressive effects. Article Title: Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway Article Snippet: The primary antibodies used in this experiment were Article Title: Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Article Snippet: Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites.. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM).. However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and Gentle:Article Title: Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation. Article Snippet: Adult neurogenesis in hippocampus dentate gyrus (DG) is associated with numerous neurodegenerative diseases such as aging and Alzheimer’s disease (AD).. Overactivation of microglia induced neuroinflammation is well acknowledged to contribute to the impaired neurogenesis in pathologies of these diseases and then leading to cognitive dysfunction.. Histamine H3 receptor (H3R) is a presynaptic autoreceptor regulating histamine release via negative feedback way. Article Title: Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells Article Snippet: The primary antibodies used were as follows: CREB, Phospho-CREB, p38, Phospho-p38, Article Title: Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts. Article Snippet: Mouse enzyme-linked immunosorbent assay (ELISA) kits were purchased from Boster Biological Technology, Wuhan, China; TRIzol reagent was from Ambion, Austin, TX, USA; RevertAidTM M-MuLV reverse transcriptase was from Fermentas, NY, Amherst, USA; FastStart Universal SYBR Green Master (Rox) was from Roche Diagnostics, Indianapolis, IN, USA; cyclic 3′,5′-adenosine monophosphate (cAMP) assay kit was from Jiancheng Bioengineering Institute, Nanjing, China; Fluo-3 AM was from Dojindo Laboratories, Kumamoto, Japan; reactive oxygen species (ROS) assay kit, radioimmunoprecipitation assay (RIPA) lysis buffer, enhanced chemiluminescence (ECL) kit, bicinchoninic acid (BCA) protein assay kit, horseradish peroxidase (HRP)-conjugated anti-rabbit and anti-mouse IgG were from Beyotime Biotech, Nantong, China; protease inhibitor and phosphatase inhibitor were from Bimake, Houston, TX, USA; anti-rabbit p38 MAPK, phospho-p38 MAPK, p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK, NF-κB p65, phosphor-NF-κB p65, CREB, phospho-CREB, COX2, and Article Title: Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression. Article Snippet: Ethnopharmacological relevance: Uncaria rhynchophylla ([Mi] Jack) (gouteng) exerts antidepressive effects.. Rhynchophylline (RH), a major component of U. rhynchophylla, exerts similar pharmacological effects to those of gouteng.. Thus, RH may have antidepressive effects. Article Title: Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway Article Snippet: The primary antibodies used in this experiment were Article Title: Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Article Snippet: Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites.. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM).. However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and Activation Assay:Article Title: Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation. Article Snippet: Adult neurogenesis in hippocampus dentate gyrus (DG) is associated with numerous neurodegenerative diseases such as aging and Alzheimer’s disease (AD).. Overactivation of microglia induced neuroinflammation is well acknowledged to contribute to the impaired neurogenesis in pathologies of these diseases and then leading to cognitive dysfunction.. Histamine H3 receptor (H3R) is a presynaptic autoreceptor regulating histamine release via negative feedback way. Article Title: Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells Article Snippet: The primary antibodies used were as follows: CREB, Phospho-CREB, p38, Phospho-p38, Article Title: Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts. Article Snippet: Mouse enzyme-linked immunosorbent assay (ELISA) kits were purchased from Boster Biological Technology, Wuhan, China; TRIzol reagent was from Ambion, Austin, TX, USA; RevertAidTM M-MuLV reverse transcriptase was from Fermentas, NY, Amherst, USA; FastStart Universal SYBR Green Master (Rox) was from Roche Diagnostics, Indianapolis, IN, USA; cyclic 3′,5′-adenosine monophosphate (cAMP) assay kit was from Jiancheng Bioengineering Institute, Nanjing, China; Fluo-3 AM was from Dojindo Laboratories, Kumamoto, Japan; reactive oxygen species (ROS) assay kit, radioimmunoprecipitation assay (RIPA) lysis buffer, enhanced chemiluminescence (ECL) kit, bicinchoninic acid (BCA) protein assay kit, horseradish peroxidase (HRP)-conjugated anti-rabbit and anti-mouse IgG were from Beyotime Biotech, Nantong, China; protease inhibitor and phosphatase inhibitor were from Bimake, Houston, TX, USA; anti-rabbit p38 MAPK, phospho-p38 MAPK, p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK, NF-κB p65, phosphor-NF-κB p65, CREB, phospho-CREB, COX2, and Article Title: Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression. Article Snippet: Ethnopharmacological relevance: Uncaria rhynchophylla ([Mi] Jack) (gouteng) exerts antidepressive effects.. Rhynchophylline (RH), a major component of U. rhynchophylla, exerts similar pharmacological effects to those of gouteng.. Thus, RH may have antidepressive effects. Article Title: Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway Article Snippet: The primary antibodies used in this experiment were Article Title: Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Article Snippet: Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites.. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM).. However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and Expressing:Article Title: Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation. Article Snippet: Adult neurogenesis in hippocampus dentate gyrus (DG) is associated with numerous neurodegenerative diseases such as aging and Alzheimer’s disease (AD).. Overactivation of microglia induced neuroinflammation is well acknowledged to contribute to the impaired neurogenesis in pathologies of these diseases and then leading to cognitive dysfunction.. Histamine H3 receptor (H3R) is a presynaptic autoreceptor regulating histamine release via negative feedback way. Article Title: Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells Article Snippet: The primary antibodies used were as follows: CREB, Phospho-CREB, p38, Phospho-p38, Article Title: Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts. Article Snippet: Mouse enzyme-linked immunosorbent assay (ELISA) kits were purchased from Boster Biological Technology, Wuhan, China; TRIzol reagent was from Ambion, Austin, TX, USA; RevertAidTM M-MuLV reverse transcriptase was from Fermentas, NY, Amherst, USA; FastStart Universal SYBR Green Master (Rox) was from Roche Diagnostics, Indianapolis, IN, USA; cyclic 3′,5′-adenosine monophosphate (cAMP) assay kit was from Jiancheng Bioengineering Institute, Nanjing, China; Fluo-3 AM was from Dojindo Laboratories, Kumamoto, Japan; reactive oxygen species (ROS) assay kit, radioimmunoprecipitation assay (RIPA) lysis buffer, enhanced chemiluminescence (ECL) kit, bicinchoninic acid (BCA) protein assay kit, horseradish peroxidase (HRP)-conjugated anti-rabbit and anti-mouse IgG were from Beyotime Biotech, Nantong, China; protease inhibitor and phosphatase inhibitor were from Bimake, Houston, TX, USA; anti-rabbit p38 MAPK, phospho-p38 MAPK, p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK, NF-κB p65, phosphor-NF-κB p65, CREB, phospho-CREB, COX2, and Article Title: Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression. Article Snippet: Ethnopharmacological relevance: Uncaria rhynchophylla ([Mi] Jack) (gouteng) exerts antidepressive effects.. Rhynchophylline (RH), a major component of U. rhynchophylla, exerts similar pharmacological effects to those of gouteng.. Thus, RH may have antidepressive effects. Article Title: Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway Article Snippet: The primary antibodies used in this experiment were Article Title: Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Article Snippet: Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites.. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM).. However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and Control:Article Title: Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation. Article Snippet: Adult neurogenesis in hippocampus dentate gyrus (DG) is associated with numerous neurodegenerative diseases such as aging and Alzheimer’s disease (AD).. Overactivation of microglia induced neuroinflammation is well acknowledged to contribute to the impaired neurogenesis in pathologies of these diseases and then leading to cognitive dysfunction.. Histamine H3 receptor (H3R) is a presynaptic autoreceptor regulating histamine release via negative feedback way. Article Title: Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells Article Snippet: The primary antibodies used were as follows: CREB, Phospho-CREB, p38, Phospho-p38, Article Title: Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts. Article Snippet: Mouse enzyme-linked immunosorbent assay (ELISA) kits were purchased from Boster Biological Technology, Wuhan, China; TRIzol reagent was from Ambion, Austin, TX, USA; RevertAidTM M-MuLV reverse transcriptase was from Fermentas, NY, Amherst, USA; FastStart Universal SYBR Green Master (Rox) was from Roche Diagnostics, Indianapolis, IN, USA; cyclic 3′,5′-adenosine monophosphate (cAMP) assay kit was from Jiancheng Bioengineering Institute, Nanjing, China; Fluo-3 AM was from Dojindo Laboratories, Kumamoto, Japan; reactive oxygen species (ROS) assay kit, radioimmunoprecipitation assay (RIPA) lysis buffer, enhanced chemiluminescence (ECL) kit, bicinchoninic acid (BCA) protein assay kit, horseradish peroxidase (HRP)-conjugated anti-rabbit and anti-mouse IgG were from Beyotime Biotech, Nantong, China; protease inhibitor and phosphatase inhibitor were from Bimake, Houston, TX, USA; anti-rabbit p38 MAPK, phospho-p38 MAPK, p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK, NF-κB p65, phosphor-NF-κB p65, CREB, phospho-CREB, COX2, and Article Title: Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression. Article Snippet: Ethnopharmacological relevance: Uncaria rhynchophylla ([Mi] Jack) (gouteng) exerts antidepressive effects.. Rhynchophylline (RH), a major component of U. rhynchophylla, exerts similar pharmacological effects to those of gouteng.. Thus, RH may have antidepressive effects. Article Title: Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway Article Snippet: The primary antibodies used in this experiment were Article Title: Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Article Snippet: Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites.. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM).. However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and Binding Assay:Article Title: Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation. Article Snippet: Adult neurogenesis in hippocampus dentate gyrus (DG) is associated with numerous neurodegenerative diseases such as aging and Alzheimer’s disease (AD).. Overactivation of microglia induced neuroinflammation is well acknowledged to contribute to the impaired neurogenesis in pathologies of these diseases and then leading to cognitive dysfunction.. Histamine H3 receptor (H3R) is a presynaptic autoreceptor regulating histamine release via negative feedback way. Article Title: Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells Article Snippet: The primary antibodies used were as follows: CREB, Phospho-CREB, p38, Phospho-p38, Article Title: Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts. Article Snippet: Mouse enzyme-linked immunosorbent assay (ELISA) kits were purchased from Boster Biological Technology, Wuhan, China; TRIzol reagent was from Ambion, Austin, TX, USA; RevertAidTM M-MuLV reverse transcriptase was from Fermentas, NY, Amherst, USA; FastStart Universal SYBR Green Master (Rox) was from Roche Diagnostics, Indianapolis, IN, USA; cyclic 3′,5′-adenosine monophosphate (cAMP) assay kit was from Jiancheng Bioengineering Institute, Nanjing, China; Fluo-3 AM was from Dojindo Laboratories, Kumamoto, Japan; reactive oxygen species (ROS) assay kit, radioimmunoprecipitation assay (RIPA) lysis buffer, enhanced chemiluminescence (ECL) kit, bicinchoninic acid (BCA) protein assay kit, horseradish peroxidase (HRP)-conjugated anti-rabbit and anti-mouse IgG were from Beyotime Biotech, Nantong, China; protease inhibitor and phosphatase inhibitor were from Bimake, Houston, TX, USA; anti-rabbit p38 MAPK, phospho-p38 MAPK, p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK, NF-κB p65, phosphor-NF-κB p65, CREB, phospho-CREB, COX2, and Article Title: Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression. Article Snippet: Ethnopharmacological relevance: Uncaria rhynchophylla ([Mi] Jack) (gouteng) exerts antidepressive effects.. Rhynchophylline (RH), a major component of U. rhynchophylla, exerts similar pharmacological effects to those of gouteng.. Thus, RH may have antidepressive effects. Article Title: Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway Article Snippet: The primary antibodies used in this experiment were Article Title: Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Article Snippet: Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites.. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM).. However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and Western Blot:Article Title: Histamine H3R antagonist counteracts the impaired hippocampal neurogenesis in Lipopolysaccharide-induced neuroinflammation. Article Snippet: Adult neurogenesis in hippocampus dentate gyrus (DG) is associated with numerous neurodegenerative diseases such as aging and Alzheimer’s disease (AD).. Overactivation of microglia induced neuroinflammation is well acknowledged to contribute to the impaired neurogenesis in pathologies of these diseases and then leading to cognitive dysfunction.. Histamine H3 receptor (H3R) is a presynaptic autoreceptor regulating histamine release via negative feedback way. Article Title: Molecular Mechanisms of Oxidative Stress Relief by CAPE in ARPE−19 Cells Article Snippet: The primary antibodies used were as follows: CREB, Phospho-CREB, p38, Phospho-p38, Article Title: Mechanism of Innate Immune Response Induced by Albizia julibrissin Saponin Active Fraction Using C2C12 Myoblasts. Article Snippet: Mouse enzyme-linked immunosorbent assay (ELISA) kits were purchased from Boster Biological Technology, Wuhan, China; TRIzol reagent was from Ambion, Austin, TX, USA; RevertAidTM M-MuLV reverse transcriptase was from Fermentas, NY, Amherst, USA; FastStart Universal SYBR Green Master (Rox) was from Roche Diagnostics, Indianapolis, IN, USA; cyclic 3′,5′-adenosine monophosphate (cAMP) assay kit was from Jiancheng Bioengineering Institute, Nanjing, China; Fluo-3 AM was from Dojindo Laboratories, Kumamoto, Japan; reactive oxygen species (ROS) assay kit, radioimmunoprecipitation assay (RIPA) lysis buffer, enhanced chemiluminescence (ECL) kit, bicinchoninic acid (BCA) protein assay kit, horseradish peroxidase (HRP)-conjugated anti-rabbit and anti-mouse IgG were from Beyotime Biotech, Nantong, China; protease inhibitor and phosphatase inhibitor were from Bimake, Houston, TX, USA; anti-rabbit p38 MAPK, phospho-p38 MAPK, p44/42 MAPK, phospho-p44/42 MAPK, SAPK/JNK, phospho-SAPK/JNK, NF-κB p65, phosphor-NF-κB p65, CREB, phospho-CREB, COX2, and Article Title: Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression. Article Snippet: Ethnopharmacological relevance: Uncaria rhynchophylla ([Mi] Jack) (gouteng) exerts antidepressive effects.. Rhynchophylline (RH), a major component of U. rhynchophylla, exerts similar pharmacological effects to those of gouteng.. Thus, RH may have antidepressive effects. Article Title: Thioperamide Alleviates Lipopolysaccharide-Induced Neuroinflammation and Promotes Neurogenesis by Histamine Dependent Activation of H2R/PKA/CREB Pathway Article Snippet: The primary antibodies used in this experiment were Article Title: Regulation of peroxiredoxin-3 gene expression under basal and hyperglycemic conditions: Key roles for transcription factors Sp1, CREB and NF-κB. Article Snippet: Peroxiredoxin-3 (Prx-3), a thioredoxin-dependent peroxidase located exclusively in the mitochondrial matrix, catalyses peroxides/peroxinitrites.. Altered levels of Prx-3 is associated with diabetic cardiomyopathy (DCM).. However, molecular mechanisms of Prx-3 gene regulation remain partially understood. Article Title: Ethyl Gallate Isolated from Castanopsis cuspidata var. sieboldii Branches Inhibits Melanogenesis and Promotes Autophagy in B16F10 Cells Article Snippet: Phospho-CREB (p-CREB), phospho-PKA (p-PKA), AMPK, p-AKT, AKT, p-mTOR, mTOR, Becline, and Article Title: Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis. Article Snippet: Primary-antibodies including postsynaptic density protein 95 (PSD95), Synapsin I a/b, estrogen receptor β (ERβ), heat shock proteins 60 (HSP60), heat shock proteins 70 (HSP70), and caseinolytic protease (CLPP) were purchased from Santa Cruz (Dallas, TX, USA); phospho-AMPK, AMPK, CREB and |